Diabetes & Covid - 19
Issues of Cardiovascular Risk
Management in People With
Diabetes in the COVID-19 Era
Antonio Ceriello, Eberhard Standl, Doina Catrinoiu, Baruch Itzhak, Nebojsa M. Lalic, Dario Rahelic, Oliver Schnell, Jan Skrha, and Paul Valensi,
People with diabetes compared with people without exhibit worse prognosis if
affected by coronavirus disease 2019 (COVID-19) induced by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly when compromising metabolic control and concomitant cardiovascular disorders are present.
Why is hyperglycaemia worsening COVID-19 and its prognosis?
Antonio Ceriello MD
Valeria De Nigris MD
Francesco Prattichizzo PhD
Hyperglycaemia, even in people without previous diabetes, has often been reported in the complicated coronavirus disease 2019 (COVID-19).
Hyperglycaemia in COVID-19 is a strong predictor of worsening the prognosis and increasing the possibility of death.
Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery
Francesco Rubino, Ricardo V Cohen, Geltrude Mingrone, Carel W le Roux, Jeffrey I Mechanick, David E Arterburn, Josep Vidal, George Alberti, Stephanie A Amiel, Rachel L Batterham, Stefan Bornstein, Ghassan Chamseddine, Stefano Del Prato, John B Dixon, Robert H Eckel, David Hopkins, Barbara M McGowan, An Pan, Ameet Patel, François Pattou, Philip R Schauer, Paul Z Zimmet, David E Cummings
The coronavirus disease 2019 pandemic is wreaking havoc on society, especially health-care systems, including disrupting bariatric and metabolic surgery. The current limitations on accessibility to non-urgent care undermine postoperative monitoring of patients who have undergone such operations. Furthermore, like most elective surgery, new bariatric and metabolic procedures are being postponed worldwide during the pandemic.
UK Study Under Review Finds People With Type 1 Diabetes More at Risk To Die of COVID-19 Than People With Type 2 Diabetes
By Riva Greenberg
There’s a large UK study (2 million people) under peer review that’s gaining traction on social media. Why? Because it defies our - already overtaxed mental states - of what’s possible.
COVID-19 in people living with diabetes: An international consensus
A.E. Caballero, A. Ceriello,
A. Misra, P. Aschner, M.E.
McDonnell, M. Hassanein,
L. Ji, J.C. Mbanya, V.A. Fonseca
A large proportion of patients with COVID-19 requiring hospitalization and/or succumbing to the disease have
had diabetes and other chronic conditions as underlying risk factors.
COVID-19 in people with diabetes: understanding the
reasons for worse outcomes
Matteo Apicella, Maria Cristina Campopiano, Michele Mantuano, Laura Mazoni*, Alberto Coppelli, Stefano Del Prato
Since the initial COVID-19 outbreak in China, much attention has focused on people with diabetes because of poor
prognosis in those with the infection. Initial reports were mainly on people with type 2 diabetes, although recent
surveys have shown that individuals with type 1 diabetes are also at risk of severe COVID-19. The reason for worse
prognosis in people with diabetes is likely to be multifactorial, thus reflecting the syndromic nature of diabetes.
New-Onset Diabetes in Covid-19
Francesco Rubino, M.D., Stephanie A. Amiel, M.D., Paul Zimmet, M.D., George Alberti, M.D., Stefan Bornstein, M.D., Robert H. Eckel, M.D., Geltrude Mingrone, M.D., Bernhard Boehm, M.D., Mark E. Cooper, Ph.D., Zhonglin Chai, Ph.D., Stefano Del Prato, M.D.
Linong Ji, M.D., David Hopkins, M.D.
William H. Herman, M.D., Kamlesh Khunti, M.D., Jean‑Claude Mbanya, M.D.
Eric Renard, M.D.
There is a bidirectional relationship
between Covid-19 and diabetes. On the one hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, newonset diabetes and severe metabolic complications of preexisting diabetes, including diabetic
ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.
COVID-19 infection in Italian people with diabetes: Lessons learned for our future (an experience to be used)
Sandro Gentile, Felice Strollo, Antonio Ceriello
As of today March 27, 2020, 86,499 Italian people have been found to be SARS-CoV2 (leading to COVID-19 disease) positive in terms of viral nucleic acid test results on throat swab samples after January 30, when the epidemic conventionally started based on the first documented case in our country,
i.e. Mattia
Diabetes and COVID-19: Risks,
Management, and Learnings From
Other National Disasters
Jamie Hartmann-Boyce, Elizabeth Morris,
Clare Goyder, Jade Kinton, James Perring, David Nunan,
Kamal Mahtani, John B. Buse, Stefano Del Prato, Linong Ji, Ronan Roussel, and Kamlesh Khunti10
Evidence relating to the impact of COVID-19 in people with diabetes (PWD) is limited but continuing to emerge.PWDappear to be at increased risk ofmoresevere COVID- 19 infection, though evidence quantifying the risk is highly uncertain. The extent to which clinical and demographic factors moderate this relationship is unclear, though signals are emerging that link higher BMI and higher HbA1c to worse outcomes in PWDwith COVID-19.
Diabetes during the COVID-19 pandemic: A global call
to reconnect with patients and emphasize lifestyle changes
and optimize glycemic and blood pressure control
Anoop Misra, Zachary Bloomgarden
Individuals with diabetes, obesity, and hypertension are at heightened risk of adverse outcome of coronavirus associated disease 2019 (COVID-19). Data from many studies show that patients with diabetes have increased risk of admission in intensive care units and of mortality.
1 Hypertension is highly prevalent in patients with COVID-19 and was the most common cardiovascular comorbidity in a meta-analysis, contributing to increase
in mortality.